Group B streptococcus induces trophoblast death

Group B Streptococcus induces apoptosis in macrophages.

Group B Streptococcus (GBS) is a pathogen that has developed some strategies to resist host immune defenses. Because phagocytic killing is an important pathogenetic mechanism for bacteria, we investigated whether GBS induces apoptosis in murine macrophages. GBS type III strain COH31 r/s (GBS-III) first causes a defect in cell membrane permeability, then at 24 h, apoptosis. Apoptosis was confirm...

Apoptosis by Calpain Activation Induces Macrophage Streptococcus Group B

Investigation of Betahemolytic Streptococcus Group B in Natural Vaginal Flora

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9 Group B Streptococcus Meningitis

9.1 Introduction Streptococcus agalactiae (Group B Streptococcus, GBS) is a Gram-positive encapsulated bacterium possessing an array of virulence factors that render it capable of producing serious disease in susceptible hosts, in particular the human newborn (Maisey et al., 2008a). Notably, GBS is the leading cause of meningitis in the neonatal period (Brouwer et al., 2010; Thigpen et al., 201...

Maternal Group B Streptococcus colonisation

Streptococcus agalactiae, commonly known as Group B Streptococcus (GBS), is an important neonatal pathogen known to cause sepsis, meningitis and pneumonia. Australian pregnant women undergo screening during pregnancy in an effort to eradicate GBS before delivery where transmission to the neonate can occur. Preventative treatment includes intrapartum antibiotic prophylaxis and results in widespr...